An improved collagen scaffold for skeletal regeneration
نویسندگان
چکیده
منابع مشابه
An improved collagen scaffold for skeletal regeneration.
Bone repair and regeneration is one of the most extensively studied areas in the field of tissue engineering. All of the current tissue engineering approaches to create bone focus on intramembranous ossification, ignoring the other mechanism of bone formation, endochondral ossification. We propose to create a transient cartilage template in vitro, which could serve as an intermediate for bone f...
متن کاملHealing Potential of Mesenchymal Stem Cells Cultured on a Collagen-Based Scaffold for Skin Regeneration
Background: Wound healing of burned skin remains a major goal in public health. Previous reports showed that the bone marrow stem cells were potent in keratinization and vascularization of full thickness skin wounds. Methods: In this study, mesenchymal stem cells were derived from rat adipose tissues and characterized by flowcytometry. Staining methods were used to evaluate their differentiatio...
متن کاملhealing potential of mesenchymal stem cells cultured on a collagen-based scaffold for skin regeneration
background: wound healing of burned skin remains a major goal in public health. previous reports showed that the bone marrow stem cells were potent in keratinization and vascularization of full thickness skin wounds. methods: in this study, mesenchymal stem cells were derived from rat adipose tissues and characterized by flowcytometry. staining methods were used to evaluate their differentiatio...
متن کاملEnhanced bone regeneration using an insulin-loaded nano-hydroxyapatite/collagen/PLGA composite scaffold
Insulin is widely considered as a classical hormone and drug in maintaining energy and glucose homeostasis. Recently, insulin has been increasingly recognized as an indispensable factor for osteogenesis and bone turnover, but its applications in bone regeneration have been restricted because of the short periods of activity and uncontrolled release. In this study, we incorporated insulin-loaded...
متن کاملIn vitro evaluation of a bone morphogenetic protein-2 nanometer hydroxyapatite collagen scaffold for bone regeneration
Scaffold fabrication and biocompatibility are crucial for successful bone tissue engineering. Nanometer hydroxyapatite (nHAP) combined with collagen (COL) is frequently utilized as a suitable osseous scaffold material. Furthermore, growth factors, including bone morphogenetic protein‑2 (BMP‑2), are used to enhance the scaffold properties. The present study used blending and freeze‑drying method...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biomedical Materials Research Part A
سال: 2010
ISSN: 1549-3296,1552-4965
DOI: 10.1002/jbm.a.32694